---layout: posttitle: Sugar research left a bitter tasteauthor: Joe Schwarczsource: McGill Blogs---HYPERLINK"http://blogs.mcgill.ca/oss/2016/09/25/the-right-chemistry-sugar-research-left-a-bitter-taste/" The Right Chemistry: Sugar research left abitter tasteโIs it true that putting a piece of garlic in the rectum at night cancleanse the body?โAnd with that single question posed by an audience member back in 1975,my chemical focus shifted to food and nutrition. The question came afterone of my first public talks on chemistry at a local library, where Ihad described the role chemistry plays in our daily lives, mostly usingdyes, drugs, plastics and cosmetics as examples.I was sort of taken aback by the question, but managed to stammersomething like โwhere did you hear that?โBack came the answer, โfrom Panic in the Pantry.โ After mentioningthat my only experience with garlic had been with rubbing it on toastwith some very satisfying results to the palate, I promised to check outthe reference.It wasnโt hard to track down Panic in the Pantry in a local bookstore.The title had suggested some sort of attack on our food system, but thisturned out not to be the case. At least not in the way I had thought.Flipping through the book I came across terms like โchemophobia,โโcarcinogen,โ โadditives,โ โchemical-freeโ and โhealthfoods.โ I was intrigued, especially on noting that the book had hadbeen written by Frederick Stare, a physician with a previous degree inchemistry who had founded the Department of Nutrition at HarvardโsSchool of Public Health, and co-authorย Elizabeth Whelan. Within a day Ihad read Panic in the Pantry from cover to cover and was so captivatedthat I dove into the turbid waters of nutrition and food chemistry withgreat enthusiasm. Ever since then, I have been trying to keep my headabove water, buffeted by the growing waves of information andmisinformation.Panic in the Pantry focused on what the authors believed wereunrealistic worries about our food supply, vigorously attacking thepopular lay notion that โif you canโt pronounce it, it must beharmful.โ Yes, that daft message was around long before the Food Babemade it her anthem. In truth, the risks and benefits of a chemical are aconsequence of its molecular structure, and are determined byappropriate studies, not by the number of syllables in its name. Stareand Whelan also challenged the โDelaney Clause,โ a piece of U.S.legislation stating that no additive shall be deemed safe if it has beenshown to cause cancer in any species upon any type of exposure. Theypointed at studies that showed very different effects of chemicals inrodents and humans and maintained that it was unrealistic to condemnadditives if exposure was not taken into account. โToo much sun cancause skin cancer, but does that mean we should stay indoors all thetime?โ they asked.What about the curious case of the clove of garlic in the rectum? Anexcellent example of a misinterpretation of information, something thatI have seen much too often. In a discussion of food faddism through theages, the authors introduced the antics of one Adolphus Hohensee, whohad forged a career as a โhealth foodโ advocate after his realestate business had landed him in jail for mail fraud. The dietary gurutold his audiences that the sex act should last an hour, and if they didnot measure up to this level of sexual adequacy it was because they hada diet laden with additives.Hohenseeโs answer to the chemical onslaught was a clove of garlic inthe rectum at night, with proof of its efficacy being the scent ofgarlic on the breath in the morning. Obviously, the garlic had workedits way from bottom to top, cleansing everything in-between. Far frompromoting this regimen, Stare and Whelan had used it to highlight theextent of nutritional quackery.I found most of the arguments in Panic in the Pantry highly palatable,but there was a discussion of one chemical that left a somewhat bittertaste. That chemical was sugar. I had been quite taken by Pure, Whiteand Deadly, a 1972 book by British physiologist John Yudkin, who made acompelling case linking sugar to heart disease, cavities, diabetes,obesity and possibly some cancers. Stare dismissed sugar as a culprit,implicating saturated fats as the cause of coronary disease. That to meseemed not to meet the standard of evidence that was applied to otherissues in Panic in the Pantry.As it turns out, there was a reason for Stareโs dismissal of sugar asa health problem. In 1965, the Sugar Research Foundation (SRF), theindustryโs trade association, asked Stare to sit on its advisory boardbecause of his expertise in the dietary causes of heart disease. Thesugar industry was extremely worried about Yudkinโs growing influenceand decided to embark on a major program to take the focus off sugar anddirect it toward fats. Stareโs defence of sugar as a quick energy foodthat should be put in coffee or tea several times a day and calling CocaCola a healthy between meals snack was welcomed by the industry.As we have now learned from historical documents brought to light in apaper in the Journal of the American Medical Association, the SRF paidmembers of Stareโs department to carry out a literature review,overseen by Stare, designed to point a finger at fats while expressingskepticism about sugarโs supposed criminality. That review waspublished in the New England Journal of Medicine without any disclosureof sugar industry funding and successfully steered readers away fromassociating sugar with heart disease. While Stare, who died in 2002, wascorrect about many aspects of unfounded chemophobia, his reputation hasnow been tarnished by the undeclared payments received by his departmentfrom the sugar industry.Sugar, as we now know, is not as innocent as Stare had claimed. But atleast he never did suggest garlic in the rectum to cleanse toxins. Asfar as I know, neither has the Food Babe.ยDr. Joe Schwarcz ย PhDSept 25th/2016